Description
Cardene, generic name nicardipine, is a calcium channel blocker primarily used to manage hypertension (high blood pressure) and angina (chest pain). It belongs to the dihydropyridine class of calcium channel blockers, exerting its effects by relaxing and dilating blood vessels, thereby reducing blood pressure and improving blood flow to the heart muscle.
Nicardipine works by blocking calcium channels in vascular smooth muscle cells, leading to vasodilation and decreased peripheral resistance. This mechanism reduces the workload of the heart and improves oxygen supply to the myocardium, making it effective in treating angina and hypertension.
Cardene is typically administered intravenously in acute situations, such as hypertensive emergencies or perioperative hypertension. Its rapid onset of action and short duration make it suitable for acute management. However, it can also be administered orally for long-term blood pressure control.
Common side effects may include headache, flushing, dizziness, and peripheral edema. Patients with certain conditions such as heart failure or liver impairment may require dose adjustments or closer monitoring when using Cardene. Overall, Cardene is an important medication in the management of hypertension and angina, particularly in acute settings.
