Description
Inegy Tablets are a medicinal product used to reduce the risk of cardiovascular events in patients with coronary heart disease (CHD) and a history of an acute coronary syndrome (ACS), whether or not they are previously treated with a statin. They contain two active ingredients, simvastatin and ezetimibe, which work in different and complementary ways to lower cholesterol.
Here are some key features:
- Simvastatin: It acts as a cholesterol-lowering agent. The main mechanism of reduction of low-density lipoprotein (LDL) cholesterol is that following inhibition of HMG-CoA reductase activity, the LDL receptor density on the liver cells is increased and this leads to an increased removal of LDL cholesterol from the plasma and increased catabolism of LDL cholesterol.
- Ezetimibe: It localizes at the brush border of the small intestine and inhibits the absorption of cholesterol via the sterol transporter, Niemann-Pick C1-Like1 (NPC1L1). This results in decreased delivery of cholesterol to the liver, reduction of hepatic cholesterol stores, and increased clearance of cholesterol from the blood.
Please consult with a healthcare professional before starting any new medication regimen.
